| Khulani Commercial High School | |
| Motto: | 'We lead, others follow' |
| Established: | c1976 |
| Type: | Public High School |
| Religion: | Christian |
| President: | Zuka Zion |
| Head Label: | Acting Head Master |
| Head: | Mrs S. Lubanga |
| Chair Label: | Governing Body |
| Street: | 9692 Bomela Rd |
| Country: | South Africa |
| Postcode: | 5219 |
| Staff: | ~50 (full-time) |
| Enrollment: | ≈1000 pupils |
| Gender: | Male & Female |
| Lower Age: | 11 |
| Upper Age: | 24 |
| Colours: | Black & white |
| Nickname: | Khulanian |
Khulani Commercial High School is a secondary school that used to specialise in Commercial education. Since the introduction of National Curriculum Statement by the public department of basic education, the school was reintroduced as a general public secondary school without any specialisation. The school is based in Mdantsane (Buffalo City Metropolitan Municipality), Eastern Cape, South Africa.[1]