| Official Name: | Khotmyzhsk |
| Native Name: | Хотмыжск |
| Native Name Lang: | ru |
| Settlement Type: | Settlement |
| Pushpin Map: | Russia Belgorod Oblast#Russia |
| Subdivision Type: | Country |
| Subdivision Name: | Russia |
| Subdivision Type1: | Region |
| Subdivision Name1: | Belgorod Oblast |
| Subdivision Type2: | County |
| Subdivision Type3: | District |
| Subdivision Name3: | Grayvoronsky District |
| Subdivision Type4: | Municipality |
| Utc Offset1: | +3:00 |
| Coordinates: | 50.5°N 84°W[1] |
Khotmyzhsk (Russian: Хотмыжск) is a rural locality (a settlement) in Grayvoronsky District, Belgorod Oblast, Russia. The population was 500 as of 2010.[2] There are 7 streets.
Khotmyzhsk is located 16 km east of Grayvoron (the district's administrative centre) by road. Chapayevsky is the nearest rural locality.[3]