| Official Name: | Khotmyzhsk |
| Native Name: | Хотмыжск |
| Native Name Lang: | ru |
| Settlement Type: | Selo |
| Pushpin Map: | Russia Belgorod Oblast#Russia |
| Subdivision Type: | Country |
| Subdivision Name: | Russia |
| Subdivision Type1: | Region |
| Subdivision Name1: | Belgorod Oblast |
| Subdivision Type2: | County |
| Subdivision Type3: | District |
| Subdivision Name3: | Borisovsky District |
| Subdivision Type4: | Municipality |
| Utc Offset1: | +3:00 |
| Coordinates: | 50.5833°N 86°W[1] |
Khotmyzhsk (Russian: Хотмыжск) is a rural locality (a selo) and the administrative center of Khotmyzhskoye Rural Settlement, Borisovsky District, Belgorod Oblast, Russia. The population was 1,076 as of 2010.[2] There are 26 streets.
Khotmyzhsk is located 15 km east of Borisovka (the district's administrative centre) by road. Belenkoye is the nearest rural locality.[3]