| Surname: | Khomutov |
| Native Name: | Хомутовы |
| Native Name Lang: | Russian |
| Coat Of Arms: | Homutov 7-37.jpg |
| Type: | noble family |
| Country: | Russian Empire |
| Parent House: | Clan Hamilton |
| Founded: | 17th century |
| Founder: | Thomas Hamilton |
The Khomutov family is the name of a Russian noble family of Scottish origin.
According to the family's genealogy they are descended from Thomas Hamilton, who first entered the service to the Polish–Lithuanian Commonwealth and later became a soldier in Russia. He had a son named Petr (David) Homutov.