| Khlong Yan Wildlife Sanctuary | |
| Alt Name: | เขตรักษาพันธุ์สัตว์ป่าคลองยัน |
| Iucn Category: | IV |
| Map: | Thailand |
| Location: | Surat Thani Province, Thailand |
| Nearest City: | Surat Thani |
| Coordinates: | 9.148°N 98.82°W |
| Area: | 488km2 |
| Established: | 30 December 1992 |
| Governing Body: | Wildlife Conservation Office |
Khlong Yan (Thai: คลองยัน) is a wildlife sanctuary in southern Thailand, located in the west of Surat Thani Province. It is located between the Khao Sok and Kaeng Krung National Park within the hills of the Phuket mountain range.
It covers an area of 488km2, covering area of the tambon Pak Chalui of Tha Chang district, Ta Kuk Tai and Ta Kuk Nuea of Vibhavadi, Nam Hak, Tha Khanon and Ka Pao of Khiri Rat Nikhom, and Khao Pang of Ban Ta Khun.
The wildlife sanctuary is named after the river (Khlong) Yan, a tributary of the Phum Duang River. The valley of the 70km long river marks the center of the wildlife sanctuary. The main attraction within the sanctuary is the Vibhavadi waterfall.