| Khesetoane Modjadji III | |
| Rain Queen | |
| Succession: | Rain Queen of Balobedu |
| Reign: | 1895–1959 |
| Predecessor: | Masalanabo Modjadji II |
| Successor: | Makoma Modjadji IV |
| Birth Date: | 1869 |
| Birth Place: | South African Republic in an area now in Limpopo, South Africa |
| Death Place: | Transvaal Province in an area now Limpopo, South Africa |
| Issue: | Makoma Modjadji |
| Full Name: | Khesetoane Modjadji |
| House: | Modjadji |
| Father: | Unknown |
| Mother: | Princess Leakhali Modjadji |
Khesetoane Modjadji III (18691959) became the third Rain Queen from the South African Balobedu nation of the South African Limpopo Province.[1] Khesetoane reigned from 1895 to 1959. She was preceded by Rain Queen Masalanabo Modjadji II and succeeded by Rain Queen Makoma Modjadji IV.
Khesetoane was born in the 1869 and died in 1959 age 89 or 90. In 1894 her predecessor, Masalanabo Modjadji, committed ritual suicide by ingesting a poison, Maselekwane had done the same to pass her spirit and power to the next rain queen. Khesetoane was the daughter of Masalanabo's sister and great wife, Princess Leakhali, and became the heir because Masalanabo's council had already designated it before Masalanabo's death because Masalababo was childless or without any daughters. She was the longest reigning Rain Queen for being on the throne for 64 years. She chose her daughter Makoma to become her successor. Khesetoane is believed to have cursed the rest of the Rain Queen lineage because of her refusal to commit ritual suicide when the time came upon nearing her death.