The Kharkiv Regional Committee of the Communist Party of Ukraine, commonly referred to as the Kharkiv CPU obkom, was the position of highest authority in the Kharkiv Oblast, in the Ukrainian SSR of the Soviet Union. The position was created on February 27, 1932, and abolished in August 1991. The First Secretary was a de facto appointed position usually by the Central Committee of the Communist Party of Ukraine or the First Secretary of the Republic.
| Name | Term of Office | Life years | ||
|---|---|---|---|---|
| Start | End | |||
| First Secretaries of the Oblast Committee of the Communist Party | ||||
| Roman Terekhov | February 27, 1932 | January 29, 1933 | 1890–1979 | |
| Pavel Postyshev | January 29, 1933 | June 5, 1934 | 1887–1939 | |
| Mykola Demchenko | June 5, 1934 | September 21, 1936 | 1896–1937 | |
| Sergei Kudryavtsev | September 21, 1936 | February 5, 1937 | 1903–1938 | |
| Mykola Hykalo | February 5, 1937 | October 1937 | 1897–1938 | |
| Oleksandr Osypov | October 1937 | December 1938 | 1899–193. | |
| Oleksiy Frolkov | December 1938 | March 17, 1940 | ||
| Oleksiy Yepishev | March 20, 1940 | April 1942 | 1908–1985 | |
| Nazi German occupation (1941–1943) | ||||
| Illya Profatilov | 1943 | 1944 | 1906–1975 | |
| Viktor Churayev | 1944 | June 1948 | 1904–1982 | |
| Borys Koval | June 1948 | December 1948 | 1903–1959 | |
| Viktor Churayev | December 1948 | April 1950 | 1904–1982 | |
| Nikolai Podgorny | 1950 | 1953 | 1903–1983 | |
| Vitaliy Titov | July 1953 | March 2, 1961 | 1907–1980 | |
| Mykola Sobol | March 2, 1961 | July 1963 | 1910–1991 | |
| Borys Voltovsky | January 8, 1963 | December 1964 | 1906–1983 | |
| Hryhoriy Vashchenko | July 1963 | June 15, 1972 | 1920–1990 | |
| Ivan Sokolov | June 15, 1972 | February 1976 | 1928–1982 | |
| Ivan Sakhnyuk | February 1976 | June 10, 1980 | 1927– | |
| Vladyslav Mysnychenko | June 10, 1980 | January 5, 1990 | 1929– | |
| Anatoliy Myalytsya | January 5, 1990 | August 1991 | 1940– | |