| Official Name: | Khan Shaykhun Subdistrict |
| Native Name: | ناحية خان شيخون |
| Native Name Lang: | ar |
| Settlement Type: | Nahiyah |
| Pushpin Map: | Syria |
| Pushpin Label Position: | bottom |
| Pushpin Mapsize: | 250 |
| Pushpin Map Caption: | Location in Syria |
| Subdivision Type: | Country |
| Subdivision Type1: | Governorate |
| Subdivision Name1: | Idlib |
| Subdivision Type2: | District |
| Subdivision Name2: | Maarrat al-Nu'man District |
| Population As Of: | 2004 |
| Population Total: | 50469 |
| Population Blank1 Title: | Ethnicities |
| Timezone: | EET |
| Utc Offset: | +2 |
| Timezone Dst: | EEST |
| Utc Offset Dst: | +3 |
| Blank Name Sec1: | Nahya pcod |
| Blank Info Sec1: | SY070201 |
Khan Shaykhun Subdistrict (Arabic: ناحية خان شيخون) is a Syrian nahiyah (subdistrict) located in Ma'arrat al-Nu'man District in Idlib. According to the Syria Central Bureau of Statistics (CBS), Khan Shaykhun Subdistrict had a population of 50469 in the 2004 census.[1]