The First Secretary of the Khakassian regional branch of the Communist Party of the Soviet Union was the position of highest authority in the Khakassian NO (1925–1930), Khakassian AO (1930–1991) and the Khakassian ASSR (1991) in the Russian SFSR of the Soviet Union. The position was created in September 1925, and abolished on August 23, 1991. The First Secretary was a de facto appointed position usually by the Politburo or the General Secretary himself.
| Name | Term of Office | Life years | ||
|---|---|---|---|---|
| Start | End | |||
| First Secretaries of the Oblast Committee of the Communist Party | ||||
| Yegor Shurygin | November 1925 | 1927 | ||
| A.F. Kemerov | 1927 | 1929 | ||
| A.I. Ryazanov | 1930? | November 1931 | ||
| Sergey Sizykh | November 1931 | February 9, 1937 | 1902–1938 | |
| Boris Kubasov | February 9, 1937 | October 20, 1937 | 1898– | |
| Zakhar Borisovich Khayms | November 1937 | May 1938 | 1899–1942 | |
| ? | 1938 | 1939 | ||
| Konstantin Kulikov | 1939 | ? | 1910–1969 | |
| A. Naumov | 1941? | ? | ||
| Dmitry Ivanchenko | 1942? | ? | ||
| Fyodor Afanasyev | 1944 | 1948? | ||
| Taras Nemezhikov | 1948 | 1952 | 1914–1960 | |
| Nikolay Gudilin | 1952 | 1954 | 1911–? | |
| Vlas Kolpakov | 1954 | 1959 | 1909–? | |
| Ilya Strakhov | July 1959 | 1961 | 1912–1984 | |
| Aleksandr Dankovtsev | 1961 | October 13, 1971 | 1913–1971 | |
| Aleksey Krylov | November 16, 1971 | May 31, 1982 | 1928– | |
| Victor Plisov | May 31, 1982 | June 1983 | 1935– | |
| Yevgeny Yeliseyev | June 1983 | November 4, 1985 | 1936– | |
| Oleg Shenin | November 4, 1985 | October 30, 1987 | 1937–2009 | |
| Gennady Kazmin | October 30, 1987 | August 1990 | 1934– | |
| Valery Abramenko | August 1990 | August 15, 1991 | 1950– | |
| M.V. Zaytsev | August 15, 1991 | August 1991 | ||