Khabarovsk virus explained

Khabarovsk virus (KBR) is a orthohantavirus in the Bunyavirales order isolated from Microtus fortis discovered in far-east Russia. It is an enveloped, negative-sense RNA virus.^[1]

Virology

Two strains of KBR were isolated in Microtus fortis trapped in the Khabarovsk region of far-eastern Russia. The nucleotide sequences revealed that the two isolates were closely related to each other but distinct from all other hantaviruses. Phylogenetic analysis showed that these strains form a separate branch in the Hantavirus tree, positioned between the branches of Prospect Hill and Puumala viruses. Puumala virus was the closest relative, both genetically and serologically.^{[1] [2] [3]}

See also

• RNA virus
• Puumala virus

External links

• CDC's Hantavirus Technical Information Index page
• Virus Pathogen Database and Analysis Resource (ViPR): Bunyaviridae

Notes and References

1. Hörling J, Chizhikov V, Lundkvist A, Jonsson M, Ivanov L, Dekonenko A, Niklasson B, Dzagurova T, Peters CJ, Tkachenko E, Nichol S.Khabarovsk virus: a phylogenetically and serologically distinct hantavirus isolated from Microtus fortis trapped in far-east Russia. J Gen Virol. 1996 Apr;77 (Pt 4):687–94.
2. Plyusnin, A., Vapalahti, O., Ufves, K., et al. Sequences of wil Puumala virus genes show a correlation of genetic variation with geographic origin of the strains. Journal of General Virology 75, 405–409.
3. Reip, A., Haring, B., Sibold, C., et al. Coding strategy of the M and S genomic segments of a hantavirus representing a new subtype of the Puumala virus serotype. Archives of Virology 140, 2011–2026.