Hepatic fructokinase explained

Ketohexokinase
Ec Number:2.7.1.3
Cas Number:9030-50-6

Hepatic fructokinase (or ketohexokinase) is an enzyme that catalyzes the phosphorylation of fructose to produce fructose-1-phosphate.

ATP +  

\longrightarrow

  ADP +

ATP + D-fructose → ADP + D-fructose-1-phosphate[1]

Pathology

A deficiency is associated with essential fructosuria.

References

  1. Bais R, James HM, Rofe AM, Conyers RA . The purification and properties of human liver ketohexokinase. A role for ketohexokinase and fructose-bisphosphate aldolase in the metabolic production of oxalate from xylitol . Biochem. J. . 230 . 1 . 53–60 . 1985 . 2996495 . 10.1042/bj2300053. 1152585.