Ketocaine Explained

Ketocaine (INN) (brand name Vericaina, former developmental code name Astra 2358 or A-2358) is an amino ether local anesthetic of the butyrophenone family used topically for pain relief. It is marketed in Italy.[1] [2] [3]

Synthesis

Williamson ether synthesis between 2'-hydroxybutyrophenone [2887-61-8] (1) and diisopropylaminoethyl chloride hydrochloride [4261-68-1] (2) gives Ketocaine (3)..

Notes and References

  1. Book: Elks J. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. 14 November 2014. Springer. 978-1-4757-2085-3. 720–. 3 October 2016. 10 January 2023. https://web.archive.org/web/20230110131052/https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA720. live.
  2. Book: Morton IK, Hall JM . Concise Dictionary of Pharmacological Agents: Properties and Synonyms. 6 December 2012. Springer Science & Business Media. 978-94-011-4439-1. 159–.
  3. Book: Woolfson D, McCafferty D . Percutaneous Local Anaesthesia. 1 March 1993. CRC Press. 978-0-13-656372-3. 88–.

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