Keith R. Jerome Explained

Keith R. Jerome
Fields:Virology
Workplaces:University of Washington
Education:Georgetown College
Duke University
Thesis1 Title:and
Thesis2 Title:)-->
Thesis1 Url:and
Thesis2 Url:)-->
Thesis1 Year:and
Thesis2 Year:)-->
Doctoral Advisors:)-->
Spouses:)-->
Partners:)-->

Keith R. Jerome is an American virologist whose research focuses on viruses such as herpes simplex, HIV and hepatitis B that persist in their hosts. He published on the first known case of COVID-19 in the United States detecting SARS-CoV-2 in Washington State[1] and helped forge the nation's COVID-19 testing.[2] [3] [4] In 2021, Jerome and Alexander Greninger shared the Washington Innovator of the Year award for developing the laboratory based assay for detecting COVID-19.[5] He was senior author on a research article published in Science describing the cryptic transmission of SARS-CoV-2 alongside Trevor Bedford, Alexander Greninger, Jay Shendure, and Helen Chu.[6] Regarding the origin of SARS-CoV-2 he reported that the live market in Wuhan was more likely than a lab leak of the virus.[7]

Jerome studies the ways in which these viruses evade the immune system and potential therapies for these infections. Jerome and his colleagues study the uses of precision gene-editing tools like CRISPR/Cas9 to remove damaging viral genes that have tucked themselves into a person's genetic code or to insert genes that can protect cells from invading viruses. He has been working for years on research aimed at a cure for Herpes virus by using the DNA-cutting tools of gene therapy. Initial research showed these techniques could knock out small quantities of latent virus.[8] He and his colleagues are exploring this approach in combination with blood stem cell transplants as a means of curing HIV.

Academic and medical appointments

Education and training

Selected publications

Notes and References

  1. Covid-19 in Critically Ill Patients in the Seattle Region - Case Series. Pavan K.. Bhatraju. Bijan J.. Ghassemieh. Michelle. Nichols. Richard. Kim. Keith R.. Jerome. Arun K.. Nalla. Alexander L.. Greninger. Sudhakar. Pipavath. Mark M.. Wurfel. Laura. Evans. Patricia A.. Kritek. T. Eoin. West. Andrew. Luks. Anthony. Gerbino. Chris R.. Dale. Jason D.. Goldman. Shane. O'Mahony. Carmen. Mikacenic. May 21, 2020. The New England Journal of Medicine. 382. 21. 2012–2022. 10.1056/NEJMoa2004500. 32227758. 7143164.
  2. Web site: How UW's Virology Lab Helped Forge the Nation's Covid-19 Testing. Seattle Met.
  3. Web site: When Coronavirus Struck Seattle, This Lab Was Ready To Start Testing. NPR.
  4. The race to unravel the biggest coronavirus outbreak in the United States. Amy. Maxmen. March 6, 2020. Nature. 579. 7798. 181–182. 10.1038/d41586-020-00676-3. 32152595. 2020Natur.579..181M. 212655031.
  5. Web site: Innovator of the Year awarded to directors of virology lab. April 28, 2021. newsroom.uw.edu.
  6. Cryptic transmission of SARS-CoV-2 in Washington state. Trevor. Bedford. Alexander L.. Greninger. Pavitra. Roychoudhury. Lea M.. Starita. Michael. Famulare. Meei-Li. Huang. Arun. Nalla. Gregory. Pepper. Adam. Reinhardt. Hong. Xie. Lasata. Shrestha. Truong N.. Nguyen. Amanda. Adler. Elisabeth. Brandstetter. Shari. Cho. Danielle. Giroux. Peter D.. Han. Kairsten. Fay. Chris D.. Frazar. Misja. Ilcisin. Kirsten. Lacombe. Jover. Lee. Anahita. Kiavand. Matthew. Richardson. Thomas R.. Sibley. Melissa. Truong. Caitlin R.. Wolf. Deborah A.. Nickerson. Mark J.. Rieder. Janet A.. Englund. James. Hadfield. Emma B.. Hodcroft. John. Huddleston. Louise H.. Moncla. Nicola F.. Müller. Richard A.. Neher. Xianding. Deng. Wei. Gu. Scot. Federman. Charles. Chiu. Jeffrey S.. Duchin. Romesh. Gautom. Geoff. Melly. Brian. Hiatt. Philip. Dykema. Scott. Lindquist. Krista. Queen. Ying. Tao. Anna. Uehara. Suxiang. Tong. Duncan. MacCannell. Gregory L.. Armstrong. Geoffrey S.. Baird. Helen Y.. Chu. Jay. Shendure. Keith R.. Jerome. October 30, 2020. Science. 370. 6516. 571–575. 10.1126/science.abc0523. 32913002. 7810035.
  7. Web site: UW Medicine's head of Virology: Live market 'more likely the start' of COVID. November 28, 2021. MyNorthwest.com.
  8. Web site: Russell . Sabin . A cure for herpes? There is progress to report . Fred Hutch . 2020-08-18 . 2022-04-03.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Keith R. Jerome".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.