Kedougou virus explained

Kedougou virus (KEDV) is an arbovirus of the Flaviviridae family, genus Flavivirus, belongs to the IV group of a ((+) ssRNA) viruses.^[1] The virus was first isolated from Aedes minutus mosquitoes in Senegal in 1971.^[2] KEDV belongs to the Kedougou virus group. It is endemically present in the Kédougou Region, from which it takes its name, together with other arboviruses of the genus Flavivirus such as: Yellow fever virus (YFV), West Nile virus (WNV) and Zika virus (ZIKV).^[3] KEDV has also been isolated from Aedes circumluteolus mosquitoes collected in, KwaZulu-Natal, South Africa.^[4]

While there is serological evidence for previous infection in humans, and one isolate from humans identified in the Central African Republic, to date no disease has been reported.^[4]

Notes and References

1. Simmonds P, Becher P, Bukh J, Gould EA, Meyers G, Monath T . etal. ICTV Virus Taxonomy Profile: Flaviviridae. . J Gen Virol . 2017 . 98 . 1 . 2–3 . 28218572 . 10.1099/jgv.0.000672 . 5370391 .
2. Robin Y, Cornet M, Le Gonidec G, Chateau R, Heme G. [Kedougou virus (Ar D14701): a new Arbovirus ("Flavivirus") isolated in Senegal (author's transl)]. ]. Ann Microbiol (Paris) . 1978 . 129 . 2 . 239–44 . 677616 .
3. Sow A, Loucoubar C, Diallo D, Faye O, Ndiaye Y, Senghor CS . etal. Concurrent malaria and arbovirus infections in Kedougou, southeastern Senegal. . Malar J . 2016 . 15 . 47 . 26821709 . 10.1186/s12936-016-1100-5 . 4730666 . free.
4. Jansen van Vuren P, Parry R, Khromykh AA, Paweska JT. A 1958 Isolate of Kedougou Virus (KEDV) from Ndumu, South Africa, Expands the Geographic and Temporal Range of KEDV in Africa. . Viruses . 2021 . 13 . 7 . 1368 . 34372574 . 10.3390/v13071368 . 8309962 . free .