| Kayupulau | |
| States: | Indonesia |
| Region: | Jayapura, Papua |
| Ethnicity: | Kayu Pulau and Kayu Batu |
| Speakers: | 50 |
| Date: | 2000 |
| Ref: | e18 |
| Familycolor: | Austronesian |
| Fam2: | Malayo-Polynesian |
| Fam3: | Oceanic |
| Fam4: | Western Oceanic |
| Fam5: | North New Guinea |
| Fam6: | Sarmi – Jayapura Bay |
| Fam7: | Jayapura Bay |
| Iso3: | kzu |
| Glotto: | kayu1243 |
| Glottorefname: | Kayupulau |
Kayupulau or Kayo Pulau is a nearly extinct Austronesian language spoken mainly by adults in Jayapura Harbor in Papua province, Indonesia. By 2007, it was used by less than a tenth of the ethnic population.