| Kavala Prefecture | |
| Native Name: | Νομός Καβάλας |
| Settlement Type: | Former prefecture |
| Map Caption1: | Location of municipalities within Kavala Prefecture Prefecture |
| Subdivision Type: | Country |
| Subdivision Name: | Greece |
| Subdivision Type1: | Periphery |
| Parts Type: | Subdivisions |
| Established Title: | Established |
| Established Date: | 1915 |
| Extinct Title: | Disestablished |
| Extinct Date: | 2011 |
| Seat Type: | Capital |
| Seat: | Kavala |
| Unit Pref: | Metric |
| Area Rank: | List of the prefectures of Greece by area |
| Population Density Km2: | auto |
| Population Rank: | List of the prefectures of Greece by population |
| Postal Code Type: | Postal codes |
| Area Code Type: | Area codes |
Kavala Prefecture (Greek, Modern (1453-);: Νομός Καβάλας) was one of the prefectures of Greece. Its capital was Kavala. It was established in 1915, soon after its territory was incorporated into Greece in the Balkan Wars. The prefecture was disbanded on 1 January 2011 by the Kallikratis programme, and split into the regional units of Kavala and Thasos.