Katherine A. Fitzgerald Explained
Katherine Fitzgerald |
Birth Name: | Katherine A. Fitzgerald |
Birth Place: | Ireland |
Citizenship: | United States of America |
Alma Mater: | University College Cork, Trinity College Dublin |
Thesis Title: | Signal transduction processes regulating CD44 expression and CD44-mediated changes in pro-inflammatory gene expression |
Thesis Url: | https://www.worldcat.org/oclc/ |
Thesis Year: | 1999 |
Katherine A. Fitzgerald is an Irish-born American molecular biologist and virologist.[1] She is a professor of medicine currently working in the Division of Infectious Disease at the University of Massachusetts Medical School. She is also the director of the Program in Innate Immunity.[2]
Education
Fitzgerald received her B.Sc. degree in biochemistry in 1995 from University College Cork. She received her Ph.D. in 1999 from Trinity College Dublin,[3] studying with Luke O'Neill. Following her Ph.D., she was postdoc at Trinity College Dublin until 2004 when she moved to the University of Massachusetts Medical School.[4]
Research
Fitzgerald is known for her research in the field of innate immunity and the biology behind inflammatory responses in diseases.[5] She conducts research on many aspects of innate immunity such as the molecular basis of pathogen recognition,[6] the innate immunity to malaria,[7] and the impact with diseases such as lupus or rheumatoid arthritis.[8] In 2021, Fitzgerald published results on an antiviral option to block replication in SARS-CoV-2, the viral agent responsible for COVID-19.[9]
Awards and honors
In 2011, Fitzgerald was a finalist for the Vilcek Prize for Creative Promise in Biomedical Science.[10] In 2015, she was awarded the Science Foundation Ireland (SFI) St. Patrick's Day Science Medal, and she is the first woman to win the award.[11] She has been recognized by Clarivate as a Highly Cited Researcher in the field of immunology by Clarivate every year from 2014 to 2021 for being in the top 1% of authors cited in her field.[12] [13] In 2020, she was admitted into the Royal Irish Academy, one of Ireland's most prestigious academic bodies,[14] [15] and was elected to the American Academy of Microbiology.[16] In 2021 she was elected to the United States' National Academy of Sciences[17] and the National Academy of Medicine.[18]
Selected publications
- Fitzgerald. Katherine A.. Palsson-McDermott. Eva M.. Bowie. Andrew G.. Jefferies. Caroline A.. Mansell. Ashley S.. Brady. Gareth. Brint. Elizabeth. Dunne. Aisling. Gray. Pearl. Harte. Mary T.. McMurray. Diane. 2001. Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature. en. 413. 6851. 78–83. 10.1038/35092578. 11544529. 2001Natur.413...78F. 4333764. 0028-0836.
- Fitzgerald. Katherine A.. Rowe. Daniel C.. Barnes. Betsy J.. Caffrey. Daniel R.. Visintin. Alberto. Latz. Eicke. Monks. Brian. Pitha. Paula M.. Golenbock. Douglas T.. 2003-10-06. LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF. Journal of Experimental Medicine. en. 198. 7. 1043–1055. 10.1084/jem.20031023. 1540-9538. 2194210. 14517278.
- Hornung. Veit. Ablasser. Andrea. Charrel-Dennis. Marie. Bauernfeind. Franz. Horvath. Gabor. Caffrey. Daniel. R.. Latz. Eicke. Fitzgerald. Katherine A.. 2009. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature. en. 458. 7237. 514–518. 10.1038/nature07725. 0028-0836. 2726264. 19158675. 2009Natur.458..514H.
External links
Notes and References
- Web site: Dr. Katherine A. Fitzgerald, Ph.D.. 2014-06-21. The Milstein Awards. en-US. 2019-10-22.
- Web site: 22 October 2014. Program in Innate Immunity. September 28, 2020.
- Signal transduction processes regulating CD44 expression and CD44-mediated changes in pro-inflammatory gene expression. 1999. English. Katherine. Fitzgerald. 842504391.
- Web site: 2016-08-23. Principal Investigator. 2021-10-02. UMass Chan Medical School. en.
- Web site: 2016-08-02. Katherine Fitzgerald focuses on novel discoveries in innate immunity. 2019-10-22. University of Massachusetts Medical School. en.
- Paludan. Søren R.. Bowie. Andrew G.. Horan. Kristy A.. Fitzgerald. Katherine A.. 2011. Recognition of herpesviruses by the innate immune system. Nature Reviews Immunology. en. 11. 2. 143–154. 10.1038/nri2937. 1474-1733. 3686362. 21267015.
- Gazzinelli. Ricardo T.. Kalantari. Parisa. Fitzgerald. Katherine A.. Golenbock. Douglas T.. 2014. Innate sensing of malaria parasites. Nature Reviews Immunology. en. 14. 11. 744–757. 10.1038/nri3742. 25324127. 23050925. 1474-1733.
- Web site: 2015. Richter, Fitzgerald named to newly endowed chairs. UMass Medical School.
- Humphries. Fiachra. Shmuel-Galia. Liraz. Jiang. Zhaozhao. Wilson. Ruth. Landis. Philip. Ng. Sze-Ling. Parsi. Krishna Mohan. Maehr. Rene. Cruz. John. Morales. Angel. Ramanjulu. Joshi M.. 2021-05-18. A diamidobenzimidazole STING agonist protects against SARS-CoV-2 infection. Science Immunology. 6. 59. eabi9002. 10.1126/sciimmunol.abi9002. 8158975. 34010139.
- Web site: The Vilcek Foundation -. www.vilcek.org. 2015-11-12.
- Web site: Irish researcher Katherine Fitzgerald receives St Patrick's Day Science Medal - Discovery siliconrepublic.com - Ireland's Technology News Service. O’Connell. Claire. 2015-03-16. Silicon Republic. en. 2019-10-22.
- Web site: Megan. Bard. February 4, 2016. Fitzgerald named again in Thomson Reuters Report on most influential scientific minds.
- Pressestelle . BVDD . January 2022 . Prof. Dirk Schadendorf als "Highly Cited Researcher" ausgezeichnet . Der Deutsche Dermatologe . 70 . 1 . 71 . 10.1007/s15011-022-4872-7 . 246155863 . 0340-8078.
- Web site: 7 January 2020. Royal Irish Academy - Katherine Fitzgerald.
- Web site: Spencer. Susan. 2020. UMMS immunologist Katherine Fitzgerald admitted to Royal Irish Academy.
- Web site: 2020-02-24. Katherine Fitzgerald and Sanjay Ram elected to American Academy of Microbiology. 2021-10-02. UMass Chan Medical School. en.
- Web site: News from the National Academy of Sciences. 26 April 2021. 2 July 2021. Newly elected members and their affiliations at the time of election are: ... Fitzgerald, Katherine A.; professor, department of medicine, and Worcester Foundation for Biomedical Research Chair, University of Massachusetts Medical School, Worcester.
- Web site: National Academy of Medicine Elects 100 New Members . National Academy of Medicine . October 18, 2021 . October 18, 2021.