| Official Name: | Karlievo |
| Native Name: | Карлиево |
| Settlement Type: | Village |
| Subdivision Type: | Country |
| Subdivision Type1: | Provinces (Oblast) |
| Timezone: | EET |
| Utc Offset: | +2 |
| Timezone Dst: | EEST |
| Utc Offset Dst: | +3 |
| Pushpin Map: | Bulgaria |
| Pushpin Map Caption: | Location of Karlievo |
| Leader Title: | Mayor |
| Postal Code Type: | Postal Code |
| Subdivision Name1: | Sofia Province |
| Population Total: | 245 |
| Population Footnotes: | [1] |
| Population As Of: | 2007-01-01 |
| Population Density Km2: | auto |
| Area Total Km2: | 18.097 |
| Elevation M: | 635 |
| Postal Code: | 2088 |
| Coordinates: | 42.6833°N 31°W |
| Leader Name: | Ivan Ivanov |
| Leader Party: | BSP |
Karlievo (Bulgarian: Карлиево) is a village in western Bulgaria. It is located in the municipality of Zlatitsa, in Sofia Province. As of 2007 the village had 245 inhabitants.
Karlievo is situated in a mountainous region in the Sredna Gora mountains. The nearest village is Chelopech at 2 km to the west. Most of the population is employed in the large copper and gold mines in the surrounding region or in Cumerio Med between Zlatitsa and Pirdop - the largest copper smelter and refinery in the Balkan peninsula.