Karl Broman Explained
Karl Broman is a professor at the University of Wisconsin - Madison (UWM) in the Biostatistics and Medical Informatics departments.[1] He has been employed at UWM since 2007 and previously was employed at Johns Hopkins University from 1999 - 2007. Broman's original research focus was quantitative genetics,[2] although he has also become known for his work on reproducible research.[3] In 2016, Broman was named a Fellow of the American Statistical Association.
Research
Study of Bile Acids
In 2019 Karl Broman and a group of researchers published a study which found genetic variants in mice that impacted the bile acid levels in their guts.[4]
Broman's other highly-cited papers include:
- Broman, Karl W., et al. "Comprehensive human genetic maps: individual and sex-specific variation in recombination." The American Journal of Human Genetics 63.3 (1998): 861-869.
- Broman, Karl W., et al. "R/qtl: QTL mapping in experimental crosses." Bioinformatics 19.7 (2003): 889-890.
- Churchill, Gary A., et al. "The Collaborative Cross, a community resource for the genetic analysis of complex traits." Nature genetics 36.11 (2004): 1133.
Rstudio
Karl Broman created R (programming language) packages such as qtlcharts, QTL, and QTL2. These packages perform trait localization and visualizations of genetic data in high dimensions.
Notes and References
- Web site: Karl W Broman (0000-0002-4914-6671). ORCID. orcid.org. en. 2020-04-01.
- Web site: Karl Broman. resources.rstudio.com. en-US. 2020-04-01.
- Web site: Get With the Program. The Scientist Magazine®. en. 2020-06-01.
- Web site: Study of bile acids links individual's genetics and microbial gut community: Gene identified in mice affects both size of a bacterial population and bile acid levels in blood. ScienceDaily. en. 2020-04-01.
