| Karl Andreas Hofmann | |
| Birth Date: | 1870 4, df=y |
| Birth Place: | Ansbach, Germany |
| Death Place: | Berlin-Charlottenburg, Germany |
| Field: | solid state chemistry |
| Education: | University of Munich |
| Work Institution: | University of Munich University of Tübingen Technische Universität Berlin |
| Doctoral Advisor: | Adolf von Baeyer |
| Doctoral Students: | Ulrich Hofmann |
| Known For: | Hofmann clathrates Hofmann–Sand reaction |
| Children: | Ulrich Hofmann |
Karl Andreas Hofmann (2 April 1870 - 15 October 1940) was a German inorganic chemist.[1] He is best known for his discovery of a family of clathrates which consist of a 2-D metal cyanide sheet, with every second metal also bound axially to two other ligands. These materials have been named 'Hofmann clathrates' in his honour.