| Birth Date: | 30 June 1930 |
| Birth Place: | Germany |
| Position: | Forward |
| Youthyears1: | 1945–1949 |
| Youthclubs1: | SG Volkspolizei Greifswald |
| Youthyears2: | 1949–1950 |
| Youthclubs2: | SG Volkspolizei Schwerin |
| Years1: | 1950–1954 |
| Clubs1: | SG Dynamo Dresden |
| Years2: | 1954–1957 |
| Clubs2: | SC Dynamo Berlin |
| Years3: | 1957–1965 |
| Clubs3: | BSG Einheit Greifswald |
| Nationalyears1: | 1954 |
| Nationalteam1: | East Germany |
| Nationalcaps1: | 1 |
| Nationalgoals1: | 0 |
Karl-Heinz Holze (30 June 1930 – 11 June 2000) was a German footballer. He was one of the top goal scorers of SC Dynamo Berlin in the 1954-55 DDR-Oberliga.