| Karl-Heinz Handschuh | |
| Height: | 1.76 m |
| Birth Date: | 1947 11, df=yes |
| Birth Place: | Reichenbach, Germany |
| Position: | Midfielder, striker |
| Youthclubs1: | VfB Reichenbach |
| Years1: | 1966–1974 |
| Clubs1: | VfB Stuttgart |
| Caps1: | 185 |
| Goals1: | 64 |
| Years2: | 1974–1980 |
| Clubs2: | Eintracht Braunschweig |
| Caps2: | 173 |
| Goals2: | 22 |
| Totalcaps: | 358 |
| Totalgoals: | 86 |
| Nationalyears1: | 1972–1975 |
| Nationalcaps1: | 2 |
| Nationalgoals1: | 0 |
Karl-Heinz Handschuh (born 30 November 1947) is a German former professional footballer who played as a midfielder or striker.[1] He spent 14 seasons in the Bundesliga with VfB Stuttgart and Eintracht Braunschweig.
His son Steffen Handschuh appeared for VfB Stuttgart as well.