| Karimui-Nomane District | |
| Pushpin Map: | Papua New Guinea |
| Coordinates: | -6.494°N 144.819°W |
| Pushpin Label Position: | right |
| Pushpin Map Caption: | Location within Papua New Guinea |
| Subdivision Type: | Country |
| Subdivision Name: | Papua New Guinea |
| Subdivision Type1: | Province |
| Subdivision Name1: | Chimbu Province |
| Seat Type: | Capital |
| Seat: | Karimui |
| Area Total Km2: | 3474 |
| Population Total: | 52159 |
| Population As Of: | 2011 census |
| Population Density Km2: | auto |
| Demographics1 Title1: | Main languages |
| Timezone1: | AEST |
| Utc Offset1: | +10 |
Karimui-Nomane District is a district of the Simbu Province of Papua New Guinea. Its capital is Karimui. The population was 52,159 at the 2011 census.[1]