Karen Duff Explained

Karen Duff
Fields:Pathology
Cell Biology
Workplaces:University College London
Columbia University
New York University
University of South Florida
Alma Mater:University of East Anglia
Queens' College, Cambridge
Thesis Title:A study of human and murine cardiac development using molecular genetics methodology
Thesis Url:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.314981
Thesis Year:1991
Awards:Potamkin Prize (2006)
Website:Karen Duff

Karen Elizabeth Keitley Duff (born 1965) is a British scientist known for her work on Alzheimer's disease. Her most notable work focused on the development and characterization of mouse models of Alzheimer's disease amyloid deposition.[1] [2] She became Centre Director of the UK Dementia Research Institute's hub at University College London in spring 2020.[3]

She was educated at the University of East Anglia (BSc, 1987) and completed her PhD at Queens' College, Cambridge in 1991. At Cambridge she was a student of Sydney Brenner's department. She was awarded the Potamkin Prize in 2006, together with Karen Ashe and Bradley Hyman.[4] In 2020 she was awarded the British Neuroscience Association Award for Outstanding Contribution to Neuroscience.[5] She was formerly Professor of Pathology and Cell Biology at Columbia University.[6]

She has an h-index of 96 according to Google Scholar.[7]

Notes and References

  1. Holcomb L, Gordon MN, McGowan E, Yu X, Benkovic S, Jantzen P, Wright K, Saad I, Mueller R, Morgan D, Sanders S, Zehr C, O'Campo K, Hardy J, Prada CM, Eckman C, Younkin S, Hsiao K, Duff K . Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes . Nat Med . 4 . 1 . 97–100 . Jan 1998 . 9427614 . 10.1038/nm0198-097. 22491239 .
  2. Duff K, Eckman C, Zehr C, Yu X, Prada CM, Perez-tur J, Hutton M, Buee L, Harigaya Y, Yager D, Morgan D, Gordon MN, Holcomb L, Refolo L, Zenk B, Hardy J, Younkin S . Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1 . Nature . 383 . 6602 . 710–3 . Oct 1996 . 8878479 . 10.1038/383710a0. 1996Natur.383..710D . 4339658 .
  3. Web site: Right drug, right patient, right time: Unravelling clinical trial failures in dementia with Professor Karen Duff . UK Dementia Research Institute . 4 February 2021.
  4. Web site: Karen Duff Receives Prestigious Prize for Alzheimer's Research. NYU Langone Medical Center. 6 August 2014.
  5. Web site: Prizes awarded by the British Neuroscience Association The British Neuroscience Association. 2021-04-29. www.bna.org.uk.
  6. Web site: Karen Duff, Ph.D. - Professor of Pathology & Cell Biology. Columbia University. 6 August 2014.
  7. Web site: karen duff . . 14 April 2024.