Kappapapillomavirus is a genus of viruses in the family Papillomaviridae.[1] Rabbits serve as natural hosts. There are two species in this genus. Diseases associated with this genus include cutaneous and mucosal lesions.[2] [3]
The following two species are assigned to the genus:[3]
Viruses in Kappapapillomavirus are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 52-55 nm. Genomes are circular, around 8kb in length. The genome codes for 6 proteins, and has 6, 8 open reading frames.
| Genus | Structure | Symmetry ! | Capsid | Genomic arrangement | Genomic segmentation | |
|---|---|---|---|---|---|---|
| Kappapapillomavirus | Icosahedral | T=7 | Non-enveloped | Circular | Monopartite |
Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown.Rabbits serve as the natural host. Transmission routes are contact.