| Railroad Name: | Kansas Southwestern Railway |
| Marks: | KSW |
| Locale: | Kansas |
| Start Year: | 1991 |
| End Year: | 2000 |
| Hq City: | Wichita, KS |
The Kansas Southwestern Railway was a railroad in the U.S. state of Kansas. It was merged into a sister railroad company, the Central Kansas Railway, in 2000. The Central Kansas Railway was later sold to Watco Companies and became the Kansas and Oklahoma Railroad. KSW had a small roster of former Grand Trunk Western Railroad GM-Electromotive Division GP9s, 4544, 4557, 4912 and 4916. Most were painted in a red, white and blue paint scheme. Its headquarters were located in Wichita, Kansas. Much of the track was former Missouri Pacific, spun off by Union Pacific in 1991.