Kalafungin Explained

Atc Prefix:	None
Synonyms:	U-19718
Iupac Name:	(3aR,5R,11bR)-7-Hydroxy-5-methyl-3,3a,5,11b-tetrahydro-2H-benzo[''g'']furo[3,2-''c'']isochromene-2,6,11-trione
Cas Number:	11048-15-0
Pubchem:	283138
Chemspiderid:	391931
Kegg:	D04648
Unii:	7HR91T5TGW
Chembl:	1988648
C:	16
H:	12
O:	6
Smiles:	C[C@@H]1C2=C([C@@H]3[C@H](O1)CC(=O)O3)C(=O)c4cccc(c4C2=O)O
Stdinchi:	1S/C16H12O6/c1-6-11-13(16-9(21-6)5-10(18)22-16)14(19)7-3-2-4-8(17)12(7)15(11)20/h2-4,6,9,16-17H,5H2,1H3/t6-,9-,16+/m1/s1
Stdinchikey:	XUWPJKDMEZSVTP-LTYMHZPRSA-N

Kalafungin is a substance discovered in the 1960s and found to act as a broad-spectrum antibiotic in vitro. It was isolated from a strain of the bacterium Streptomyces tanashiensis.^{[1] [2]}

It is not known to be marketed anywhere in the world.^[3]

Notes and References

1. Bergy ME . Kalafungin, a new broad spectrum antibiotic. Isolation and characterization . The Journal of Antibiotics . 21 . 7 . 454–7 . July 1968 . 4303501 . 10.7164/antibiotics.21.454 . free .
2. Johnson LE, Dietz A . Kalafungin, a new antibiotic produced by Streptomyces tanashiensis strain Kala . Applied Microbiology . 16 . 12 . 1815–21 . December 1968 . 5726156 . 547777 . 10.1128/AEM.16.12.1815-1821.1968 .
3. Web site: Kalafungin search results. Drugs.com. 2021-03-31.