Kairine Explained

Kairine is a derivative of tetrahydroquinoline which was first described by Wilhelm Fischer in 1883. Its name comes from the Greek kairos, meaning "the right time".^[1] It is an antipyretic, formerly used against typhoid fever, but now largely obsolete due to severe side effects. Both kairine and its N-ethyl homolog show similar antipyretic activity.^{[2] [3] [4] [5]}

See also

• 8-Hydroxyquinoline

Notes and References

1. Book: The Origins of Chemical Names . W.E.Flood . Oldbourne Book Co Ltd . 1963 . 126.
2. Fischer . Wilhelm . On Kairine and Kairoline . New Remedies . 12 . 2 . 1883 . 41 .
3. Fruitnight . J. Henry . Kairine and Antipyrine . Medical Record . 29 . 23 . 1886 . 646–648 .
4. Bockmuhl M, Dorzbach E. Antipyretics of the tetrahydroquinoline series. Med. u. Chem. (1942) 4: 179-212.
5. Book: Slater, Leo Barney . War and Disease: Biomedical Research on Malaria in the Twentieth Century . Rutgers University Press . 2009 . 978-0-8135-4438-0 . 26.