KRT75 explained
KRT75 is a keratin gene involved in hair shaft structure in mice.[1] In chickens, mutations in KRT75 cause animals to have frizzled feathers.[2]
Notes and References
- Liu Y, Snedecor ER, Zhang X, Xu Y, Huang L, Jones EC, Zhang L, Clark RA, Roop DR, Qin C, Chen J . Correction of Hair Shaft Defects through Allele-Specific Silencing of Mutant Krt75 . The Journal of Investigative Dermatology . 136 . 1 . 45–51 . January 2016 . 26763422 . 4764097 . 10.1038/JID.2015.375 .
- Ng CS, Wu P, Foley J, Foley A, McDonald ML, Juan WT, Huang CJ, Lai YT, Lo WS, Chen CF, Leal SM, Zhang H, Widelitz RB, Patel PI, Li WH, Chuong CM. Cheng-Ming Chuong . The chicken frizzle feather is due to an α-keratin (KRT75) mutation that causes a defective rachis . PLOS Genetics . 8 . 7 . e1002748 . 2012 . 22829773 . 3400578 . 10.1371/journal.pgen.1002748 . free .