KP-1461 explained

Legal Status:	Investigational
Cas Number:	815588-85-3
Class:	Reverse transcriptase inhibitor
Pubchem:	51003457
Chemspiderid:	32702166
Drugbank:	05644
Unii:	3PEN569TJP
C:	16
H:	23
N:	4
O:	6
Smiles:	CCCCCCCOC(=O)NC1=NCN(C(=O)N1)[C@H]2C[C@@H]([C@H](O2)CO)O
Stdinchi:	1S/C16H28N4O6/c1-2-3-4-5-6-7-25-16(24)19-14-17-10-20(15(23)18-14)13-8-11(22)12(9-21)26-13/h11-13,21-22H,2-10H2,1H3,(H2,17,18,19,23,24)/t11-,12+,13+/m0/s1
Stdinchikey:	SZWIAFVYPPMZML-YNEHKIRRSA-N

KP-161 is an experimental antiviral drug being studied for the treatment of HIV/AIDS.^[1] It belongs to the class of nucleoside reverse transcriptase inhibitors.^[2]

KP-1461 is a prodrug of the active antiviral agent KP-1212.^[3]

Notes and References

1. Web site: AIDSinfo . KP-1461 . U.S. Department of Health and Human Services . 2018-09-04 . 2019-08-11 . https://web.archive.org/web/20190811180843/https://aidsinfo.nih.gov/drugs/554/kp-1461/0/patient . dead .
2. Harris K, Sergueev D, Reno J . The chemistry and biology of KP-1461, a selective nucleoside mutagen for HIV therapy . Retrovirology . December 2006 . 3 . Suppl 1 . S13 . 1716920 . 10.1186/1742-4690-3-S1-S13 . free .
3. Web site: KP-1461 . DrugBank . Canadian Institutes of Health Research .