Kelch-like protein 2 explained

Kelch-like family member 2 is a protein that in humans is encoded by the KLHL2 gene.^[1]

Further reading

• Tseng LA, Bixby JL . Interaction of an intracellular pentraxin with a BTB-Kelch protein is associated with ubiquitylation, aggregation and neuronal apoptosis . Molecular and Cellular Neurosciences . 47 . 4 . 254–64 . Aug 2011 . 21549840 . 10.1016/j.mcn.2011.04.005 . 3137755.
• Korutla L, Wang P, Jackson TG, Mackler SA . NAC1, a POZ/BTB protein that functions as a corepressor . Neurochemistry International . 2009 . 54 . 3–4 . 245–52 . 19121354 . 10.1016/j.neuint.2008.12.008 . 23462562 .
• Williams SK, Spence HJ, Rodgers RR, Ozanne BW, Fitzgerald U, Barnett SC . Role of Mayven, a kelch-related protein in oligodendrocyte process formation . Journal of Neuroscience Research . 81 . 5 . 622–31 . Sep 2005 . 16035103 . 10.1002/jnr.20588 . 31895360 .
• Dhanoa BS, Cogliati T, Satish AG, Bruford EA, Friedman JS . Update on the Kelch-like (KLHL) gene family . Human Genomics . 2013 . 7 . 1 . 13 . 23676014 . 10.1186/1479-7364-7-13 . 3658946 . free .
• Mai A, Jung SK, Yonehara S . hDKIR, a human homologue of the Drosophila kelch protein, involved in a ring-like structure . Experimental Cell Research . 300 . 1 . 72–83 . Oct 2004 . 15383316 . 10.1016/j.yexcr.2004.06.023 .
• Schumacher FR, Sorrell FJ, Alessi DR, Bullock AN, Kurz T . Structural and biochemical characterization of the KLHL3-WNK kinase interaction important in blood pressure regulation . The Biochemical Journal . 460 . 2 . 237–46 . Jun 2014 . 24641320 . 10.1042/BJ20140153 . 4019986.
• Soltysik-Espanola M, Rogers RA, Jiang S, Kim TA, Gaedigk R, White RA, Avraham H, Avraham S . Characterization of Mayven, a novel actin-binding protein predominantly expressed in brain . Molecular Biology of the Cell . 10 . 7 . 2361–75 . Jul 1999 . 10397770 . 10.1091/mbc.10.7.2361 . 25454.
• Bu X, Avraham HK, Li X, Lim B, Jiang S, Fu Y, Pestell RG, Avraham S . Mayven induces c-Jun expression and cyclin D1 activation in breast cancer cells . Oncogene . 24 . 14 . 2398–409 . Mar 2005 . 15735724 . 10.1038/sj.onc.1208466 . free .
• Takahashi D, Mori T, Wakabayashi M, Mori Y, Susa K, Zeniya M, Sohara E, Rai T, Sasaki S, Uchida S . KLHL2 interacts with and ubiquitinates WNK kinases . Biochemical and Biophysical Research Communications . 437 . 3 . 457–62 . Aug 2013 . 23838290 . 10.1016/j.bbrc.2013.06.104 .

Notes and References

1. Web site: Entrez Gene: Kelch-like family member 2 .