KIF6 explained

Kinesin family member 6 is a protein that in humans is encoded by the KIF6 gene.^[1] This gene encodes a member of the kinesin family of proteins. Members of this family are part of a multisubunit complex that functions as a microtubule motor in intracellular organelle transport.

Further reading

• Koroleva OS, Pushkov AA, Blagodatskikh KA, Baranova OA, Azizova OA, Nosikov VV, Reznichenko NE, Zateĭshchikov DA . [Association of a polymorphic marker Trp719Arg of KIF6 gene with effects of atorvastatin and simvastatin in patients with early ischemic heart disease] . Kardiologiia . 51 . 9 . 4–12 . 2011 . 21943003 .
• Bare LA, Ruiz-Narvaéz EA, Tong CH, Arellano AR, Rowland CM, Catanese JJ, Sacks FM, Devlin JJ, Campos H . Investigation of KIF6 Trp719Arg in a case-control study of myocardial infarction: a Costa Rican population . PLOS ONE . 5 . 9 . e13081 . September 2010 . 20927332 . 2947524 . 10.1371/journal.pone.0013081 . 2010PLoSO...513081B . free .
• Peng P, Lian J, Huang RS, Xu L, Huang Y, Ba Y, Yang X, Huang X, Dong C, Zhang L, Ye M, Zhou J, Duan S . Meta-analyses of KIF6 Trp719Arg in coronary heart disease and statin therapeutic effect . PLOS ONE . 7 . 12 . e50126 . 2012 . 23236363 . 3517591 . 10.1371/journal.pone.0050126 . 2012PLoSO...750126P . free .
• Akao H, Polisecki E, Kajinami K, Trompet S, Robertson M, Ford I, Jukema JW, de Craen AJ, Westendorp RG, Shepherd J, Packard C, Buckley BM, Schaefer EJ . KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly . Atherosclerosis . 220 . 2 . 456–62 . February 2012 . 22192511 . 10.1016/j.atherosclerosis.2011.11.037 .
• Liu X, Gomez-Pinillos A, Loder C, Carrillo-de Santa Pau E, Qiao R, Unger PD, Kurek R, Oddoux C, Melamed J, Gallagher RE, Mandeli J, Ferrari AC . KLF6 loss of function in human prostate cancer progression is implicated in resistance to androgen deprivation . The American Journal of Pathology . 181 . 3 . 1007–16 . September 2012 . 22819534 . 3432435 . 10.1016/j.ajpath.2012.06.008 .
• Davani S, Gozalo C, Gambert S, Chalmers D, Gambert P, Schiele F, Kantelip JP, Meneveau N . The polymorphism Trp719Arg in the kinesin-like protein 6 is associated with the presence of late outgrowth endothelial progenitor cells in acute myocardial infarction . Atherosclerosis . 210 . 1 . 48–50 . May 2010 . 20044086 . 10.1016/j.atherosclerosis.2009.11.041 .
• Hu M, Lui SS, Mak VW, Chu TT, Lee VW, Poon EW, Tsui TK, Ko GT, Baum L, Tam LS, Li EK, Tomlinson B . Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients . Pharmacogenetics and Genomics . 20 . 10 . 634–7 . October 2010 . 20679960 . 10.1097/FPC.0b013e32833de489 . 3475599 .
• Koroleva OS, Zateĭshchikov DA . [Motor protein Kinesin-6 and ischemic heart disease] . Kardiologiia . 50 . 6 . 54–62 . 2010 . 20659029 .
• Bhanushali AA, Contractor A, Shah VT, Das BR . Investigation of KIF6 Trp719Arg in a case-control study of coronary artery disease in Western Indians . Genetic Testing and Molecular Biomarkers . 15 . 12 . 883–6 . December 2011 . 21810021 . 10.1089/gtmb.2011.0079 .

Notes and References

1. Web site: Entrez Gene: Kinesin family member 6 .