KDPG-aldolase RNA motif explained

KDPG-aldolase
Symbol:KDPG-aldolase
Rfam:RF03115
Rna Type:Gene
sRNA

The KDPG-aldolase RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] KDPG-aldolase motifs are found in Enterobacteriaceae, but is not known to be bpresent in Escherichia coli.

It is ambiguous whether KDPG-aldolase RNAs function as cis-regulatory elements or whether they operate in trans. KDPG-aldolase RNAs appear to be in the 5′ untranslated regions of enterobacterial genes that are annotated as encoding aldolases of 2-keto-3-deoxy-6-phosphogluconate or 2-keto-4-hydroxyglutarate.

Notes and References

  1. Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR . Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions . Nucleic Acids Res. . 45 . 18 . 10811–10823 . October 2017 . 28977401 . 5737381 . 10.1093/nar/gkx699 .