KDM4B explained

Lysine-specific demethylase 4B is an enzyme that in humans is encoded by the KDM4B gene.^{[1] [2] [3]} KDM4B belongs to the alpha-ketoglutarate-dependent hydroxylase superfamily.

Further reading

• Nakajima D, Okazaki N, Yamakawa H, etal . Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. . DNA Res. . 9 . 3 . 99–106 . 2003 . 12168954 . 10.1093/dnares/9.3.99 . free .
• Andersson B, Wentland MA, Ricafrente JY, etal . A "double adaptor" method for improved shotgun library construction. . Anal. Biochem. . 236 . 1 . 107–13 . 1996 . 8619474 . 10.1006/abio.1996.0138 .
• Yu W, Andersson B, Worley KC, etal . Large-scale concatenation cDNA sequencing. . Genome Res. . 7 . 4 . 353–8 . 1997 . 9110174 . 10.1101/gr.7.4.353. 139146 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Grimwood J, Gordon LA, Olsen A, etal . The DNA sequence and biology of human chromosome 19. . Nature . 428 . 6982 . 529–35 . 2004 . 15057824 . 10.1038/nature02399 . 2004Natur.428..529G . free .
• Beausoleil SA, Jedrychowski M, Schwartz D, etal . Large-scale characterization of HeLa cell nuclear phosphoproteins. . Proc. Natl. Acad. Sci. U.S.A. . 101 . 33 . 12130–5 . 2004 . 15302935 . 10.1073/pnas.0404720101 . 514446 . 2004PNAS..10112130B . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Gray SG, Iglesias AH, Lizcano F, etal . Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein. . J. Biol. Chem. . 280 . 31 . 28507–18 . 2005 . 15927959 . 10.1074/jbc.M413687200 . free .
• Whetstine JR, Nottke A, Lan F, etal . Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases. . Cell . 125 . 3 . 467–81 . 2006 . 16603238 . 10.1016/j.cell.2006.03.028 . 14461740 . free .
• Katoh Y, Katoh M . Comparative integromics on JMJD2A, JMJD2B and JMJD2C: preferential expression of JMJD2C in undifferentiated ES cells. . Int. J. Mol. Med. . 20 . 2 . 269–73 . 2007 . 17611647 . 10.3892/ijmm.20.2.269. free .
• Deng P, Yuan Q, Cheng Y, etal . Loss of KDM4B exacerbates bone-fat imbalance and mesenchymal stromal cell exhaustion in skeletal aging. . Cell Stem Cell . 28. 6. 1057–1073.e7. 2021 . 33571444. 10.1016/j.stem.2021.01.010 . 8178178.

Notes and References

1. Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O . Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro . DNA Res . 5 . 6 . 355–64 . May 1999 . 10048485 . 10.1093/dnares/5.6.355 . free .
2. Katoh M, Katoh M . Identification and characterization of JMJD2 family genes in silico . Int J Oncol . 24 . 6 . 1623–8 . May 2004 . 15138608 . 10.3892/ijo.25.3.759.
3. Web site: Entrez Gene: JMJD2B jumonji domain containing 2B.