KCNK16 explained

Potassium channel subfamily K member 16 is a protein that in humans is encoded by the KCNK16 gene.^{[1] [2]} The protein encoded by this gene, K_2P16.1, is a potassium channel containing two pore-forming P domains.

See also

• Tandem pore domain potassium channel

Further reading

• Mungall AJ . The DNA sequence and analysis of human chromosome 6 . Nature . 425 . 6960 . 805–11 . 2003 . 14574404 . 10.1038/nature02055 . vanc. Palmer SA . Sims SK . 3 . Edwards . C. A. . Ashurst . J. L. . Wilming . L. . Jones . M. C. . Horton . R. . Hunt . S. E. . 2003Natur.425..805M . free .
• Strausberg RL . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2002 . 12477932 . 10.1073/pnas.242603899 . 139241 . vanc. Feingold EA . Grouse LH . 3 . Derge . JG . Klausner . RD . Collins . FS . Wagner . L . Shenmen . CM . Schuler . GD . 2002PNAS...9916899M . free .
• Goldstein SA, Bockenhauer D, O'Kelly I, Zilberberg N . Potassium leak channels and the KCNK family of two-P-domain subunits . Nat. Rev. Neurosci. . 2 . 3 . 175–84 . 2001 . 11256078 . 10.1038/35058574 . 9682396 .
• Han J, Kang D, Kim D . Functional properties of four splice variants of a human pancreatic tandem-pore K+ channel, TALK-1 . Am. J. Physiol., Cell Physiol. . 285 . 3 . C529–38 . 2003 . 12724142 . 10.1152/ajpcell.00601.2002 . 23208697 .
• Gierten J . Regulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genistein . Br. J. Pharmacol. . 154 . 8 . 1680–90 . 2008 . 18516069 . 10.1038/bjp.2008.213 . 2518462 . vanc. Ficker E . Bloehs R . 3 . Schlömer . K . Kathöfer . S . Scholz . E . Zitron . E . Kiesecker . C . Bauer . A .

Notes and References

1. Girard C, Duprat F, Terrenoire C, Tinel N, Fosset M, Romey G, Lazdunski M, Lesage F . Genomic and functional characteristics of novel human pancreatic 2P domain K(+) channels . Biochem Biophys Res Commun . 282 . 1 . 249–56 . Mar 2001 . 11263999 . 10.1006/bbrc.2001.4562 .
2. Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S . International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels . Pharmacol Rev . 57 . 4 . 527–40 . Dec 2005 . 16382106 . 10.1124/pr.57.4.12 . 7356601 .