KCNK15 explained
Potassium channel subfamily K member 15 is a protein that in humans is encoded by the KCNK15 gene.[1] [2] [3] [4]
This gene encodes K2P15.1, one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. K2P15.1 has not been shown to be a functional channel; however, it may require other non-pore-forming proteins for activity.
See also
Further reading
- Olsen JV, Blagoev B, Gnad F, etal . Global, in vivo, and site-specific phosphorylation dynamics in signaling networks . Cell . 127 . 3 . 635–48 . 2006 . 17081983 . 10.1016/j.cell.2006.09.026 . 7827573 . free .
- Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
- Deloukas P, Matthews LH, Ashurst J, etal . The DNA sequence and comparative analysis of human chromosome 20 . Nature . 414 . 6866 . 865–71 . 2002 . 11780052 . 10.1038/414865a . 2001Natur.414..865D . free .
- Karschin C, Wischmeyer E, Preisig-Müller R, etal . Expression pattern in brain of TASK-1, TASK-3, and a tandem pore domain K(+) channel subunit, TASK-5, associated with the central auditory nervous system . Mol. Cell. Neurosci. . 18 . 6 . 632–48 . 2002 . 11749039 . 10.1006/mcne.2001.1045 . 25284693 .
- Ashmole I, Goodwin PA, Stanfield PR . TASK-5, a novel member of the tandem pore K+ channel family . Pflügers Arch. . 442 . 6 . 828–33 . 2002 . 11680614 . 10.1007/s004240100620 . 27704471 .
Notes and References
- Kim D, Gnatenco C . TASK-5, a new member of the tandem-pore K(+) channel family . Biochem Biophys Res Commun . 284 . 4 . 923–30 . Jun 2001 . 11409881 . 10.1006/bbrc.2001.5064 .
- Vega-Saenz de Miera E, Lau DH, Zhadina M, Pountney D, Coetzee WA, Rudy B . KT3.2 and KT3.3, two novel human two-pore K(+) channels closely related to TASK-1 . J Neurophysiol . 86 . 1 . 130–42 . Jun 2001 . 11431495 . 10.1152/jn.2001.86.1.130. 14855672 .
- Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S . International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels . Pharmacol Rev . 57 . 4 . 527–40 . Dec 2005 . 16382106 . 10.1124/pr.57.4.12 . 7356601 .
- Web site: Entrez Gene: KCNK15 potassium channel, subfamily K, member 15.