KCNB2 explained

Potassium voltage-gated channel subfamily B member 2 is a protein that in humans is encoded by the KCNB2 gene.^{[1] [2]} The protein encoded by this gene is a voltage-gated potassium channel subunit.

Further reading

• Nyholt DR, LaForge KS, Kallela M, Alakurtti K, Anttila V, Färkkilä M, Hämaläinen E, Kaprio J, Kaunisto MA, Heath AC, Montgomery GW, Göbel H, Todt U, Ferrari MD, Launer LJ, Frants RR, Terwindt GM, de Vries B, Verschuren WM, Brand J, Freilinger T, Pfaffenrath V, Straube A, Ballinger DG, Zhan Y, Daly MJ, Cox DR, Dichgans M, van den Maagdenberg AM, Kubisch C, Martin NG, Wessman M, Peltonen L, Palotie A . 6 . A high-density association screen of 155 ion transport genes for involvement with common migraine . Human Molecular Genetics . 17 . 21 . 3318–3331 . November 2008 . 18676988 . 2566523 . 10.1093/hmg/ddn227 .
• Yan L, Figueroa DJ, Austin CP, Liu Y, Bugianesi RM, Slaughter RS, Kaczorowski GJ, Kohler MG . 6 . Expression of voltage-gated potassium channels in human and rhesus pancreatic islets . Diabetes . 53 . 3 . 597–607 . March 2004 . 14988243 . 10.2337/diabetes.53.3.597 . free .
• Hugnot JP, Salinas M, Lesage F, Guillemare E, de Weille J, Heurteaux C, Mattéi MG, Lazdunski M . 6 . Kv8.1, a new neuronal potassium channel subunit with specific inhibitory properties towards Shab and Shaw channels . The EMBO Journal . 15 . 13 . 3322–3331 . July 1996 . 8670833 . 451895 . 10.1002/j.1460-2075.1996.tb00697.x .
• Baranzini SE, Wang J, Gibson RA, Galwey N, Naegelin Y, Barkhof F, Radue EW, Lindberg RL, Uitdehaag BM, Johnson MR, Angelakopoulou A, Hall L, Richardson JC, Prinjha RK, Gass A, Geurts JJ, Kragt J, Sombekke M, Vrenken H, Qualley P, Lincoln RR, Gomez R, Caillier SJ, George MF, Mousavi H, Guerrero R, Okuda DT, Cree BA, Green AJ, Waubant E, Goodin DS, Pelletier D, Matthews PM, Hauser SL, Kappos L, Polman CH, Oksenberg JR . 6 . Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis . Human Molecular Genetics . 18 . 4 . 767–778 . February 2009 . 19010793 . 4334814 . 10.1093/hmg/ddn388 .
• Vasan RS, Larson MG, Aragam J, Wang TJ, Mitchell GF, Kathiresan S, Newton-Cheh C, Vita JA, Keyes MJ, O'Donnell CJ, Levy D, Benjamin EJ . 6 . Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study . BMC Medical Genetics . 8 . S2 . September 2007 . Suppl 1 . 17903301 . 1995617 . 10.1186/1471-2350-8-S1-S2 . free .
• Wu C, Ma MH, Brown KR, Geisler M, Li L, Tzeng E, Jia CY, Jurisica I, Li SS . 6 . Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening . Proteomics . 7 . 11 . 1775–1785 . June 2007 . 17474147 . 10.1002/pmic.200601006 . 22474278 .
• Salinas M, de Weille J, Guillemare E, Lazdunski M, Hugnot JP . Modes of regulation of shab K+ channel activity by the Kv8.1 subunit . The Journal of Biological Chemistry . 272 . 13 . 8774–8780 . March 1997 . 9079713 . 10.1074/jbc.272.13.8774 . free .

Notes and References

1. Schmalz F, Kinsella J, Koh SD, Vogalis F, Schneider A, Flynn ER, Kenyon JL, Horowitz B . 6 . Molecular identification of a component of delayed rectifier current in gastrointestinal smooth muscles . The American Journal of Physiology . 274 . 5 . G901–G911 . May 1998 . 9612272 . 10.1152/ajpgi.1998.274.5.G901 .
2. Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stühmer W, Wang X . 6 . International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels . Pharmacological Reviews . 57 . 4 . 473–508 . December 2005 . 16382104 . 10.1124/pr.57.4.10 . 219195192 .