| Type: | combo |
| Component1: | Imidacloprid |
| Class1: | Insecticide |
| Component2: | Permethrin |
| Class2: | Pyrethroid insecticide |
| Component3: | Pyriproxyfen |
| Class3: | Insecticide |
| Tradename: | K9 Advantix II |
Imidacloprid/permethrin/pyriproxyfen, sold under the trade name K9 Advantix II, is a combination insecticide product for dogs, used for the treatment and prevention of an array of common external parasites. It is effective against fleas, ticks, chewing lice and mosquitoes.[1] The active ingredients are imidacloprid, permethrin, and pyriproxyfen. This product is toxic to cats,[2] and it is not recommended to use it on dogs which share an environment with cats. The product is applied onto the skin; administration of the product into the mouth can cause adverse effects.[3]