Junenol Explained

Cas Number:472-07-1
Pubchem:6452077
Chemspiderid:4954519
Unii:Z3209PC5TC
Iupac Name:(1S,2S,4aR,8aS)-2-isopropyl-4a-methyl-8-methylene-decalin-1-ol
C:15
H:26
O:1
Smiles:CC(C)[C@@H]1CC[C@]2(CCCC(=C)[C@@H]2[C@H]1O)C
Stdinchi:InChI=1S/C15H26O/c1-10(2)12-7-9-15(4)8-5-6-11(3)13(15)14(12)16/h10,12-14,16H,3,5-9H2,1-2,4H3/t12-,13+,14-,15+/m0/s1
Stdinchikey:MSJJKJCIFIGTJY-LJISPDSOSA-N

Junenol is a sesquiterpene alcohol that has garnered interest in the field of natural product chemistry and essential oil research. This compound, along with its isomers like 10-epi-junenol, has been identified in various plant species and is known for its potential biological activities.[1] [2]

Junenol and its derivatives have been subjects of synthetic studies, with researchers developing efficient routes for their preparation from natural precursors. The presence of junenol and related compounds in essential oils contributes to the chemical variability observed in plant species, influencing their aromatic profiles and potential applications.[3] [4] As a sesquiterpene, junenol plays a role in the complex mixture of volatile organic compounds found in essential oils, which are known for their diverse biological activities.

Notes and References

  1. Cardona L, García B, Giménez JE, Pedro JR . A shorter route to the synthesis of (+)-junenol isojunenol, and their coumarate esters from (−)-santonin. . Tetrahedron . January 1992 . 48 . 5 . 851–860 . 10.1016/S0040-4020(01)88189-8 .
  2. Gou JB, Li ZQ, Li CF, Chen FF, Lv SY, Zhang YS . Molecular cloning and functional analysis of a 10-epi-junenol synthase from Inula hupehensis . Plant Physiology and Biochemistry . 106 . 288–294 . September 2016 . 27231873 . 10.1016/j.plaphy.2016.05.023 . 2016PlPB..106..288G .
  3. Romero D, Cartuche L, Valarezo E, Cumbicus N, Morocho V . Chemical Profiling, Anticholinesterase, Antioxidant, and Antibacterial Potential of the Essential Oil from Myrcianthes discolor (Kunth) McVaugh, an Aromatic Tree from Southern Ecuador . Antibiotics . 12 . 4 . March 2023 . 677 . 37107039 . 10135086 . 10.3390/antibiotics12040677 . free .
  4. Costa JS, Freitas JJ, Setzer WN, da Silva JK, Maia JG, Figueiredo PL . Variability in the Chemical Composition of Myrcia sylvatica (G. Mey) DC. Essential Oils Growing in the Brazilian Amazon . Molecules . 27 . 24 . December 2022 . 8975 . 36558108 . 9783174 . 10.3390/molecules27248975 . free .