| Event: | Judo – Men's 81 kg |
| Games: | 2016 Summer |
| Venue: | Carioca Arena 3 |
| Competitors: | 12 |
| Nations: | 12 |
| Gold: | Eduardo Avila Sanchez |
| Goldnpc: | MEX |
| Silver: | Lee Jung-min |
| Silvernpc: | KOR |
| Bronze: | Rovshan Safarov |
| Bronzenpc: | AZE |
| Bronze2: | Olexandr Kosinov |
| Bronzenpc2: | UKR |
| Prev: | 2012 |
| Next: | 2020 |
The men's 81 kg judo competition at the 2016 Summer Paralympics was held on 9 September at Carioca Arena 3.