| Fight Name: | Puerto Rico vs. Mexico |
| Fight Date: | November 6, 2010 |
| Location: | MGM Grand, Las Vegas, Nevada, U.S. |
| Titles: | WBO featherweight title |
| Fighter1: | Juan Manuel López |
| Nickname1: | "Juanma" |
| Hometown1: | Rio Piedras, Puerto Rico |
| Record1: | 29–0 (26 KO) |
| Height1: | 5 ft 7 in |
| Weight1: | 125+1/2 lb |
| Style1: | Orthodox |
| Recognition1: | WBO Featherweight Champion 2-division world champion |
| Fighter2: |  Rafael Márquez |
| Hometown2: | Mexico City, Distrito Federal, Mexico |
| Record2: | 39–5 (35 KO) |
| Height2: | 5 ft 5 in |
| Weight2: | 125+1/2 lb |
| Style2: | Orthodox |
| Recognition2: | WBO No. 2 Ranked Featherweight 2-division world champion |
| Result: | Lopez defeats Marquez via technical knockout in the eighth round |
Juan Manuel López vs Rafael Márquez, billed as Puerto Rico vs. Mexico, was a professional boxing match contested on November 6, 2010, for the WBO featherweight championship.[1] The fight was highly anticipated due to the history of competition between Mexican boxers and those from Puerto Rico.
The fight was originally scheduled for September 18 but postponed due to an injury Marquez sustained on his right thumb. The fight was rescheduled for November 6, which was Lopez's second defense of his WBO title and was broadcast on Showtime.[2]
Marquez lost the fight in the 8th round by TKO after he was unable to continue due to a shoulder injury. Marquez had chosen to proceed with the bout even though he suffered with a right shoulder injury before the contest because he did not wish to cause a second delay. It was later revealed that Marquez had suffered a hairline fracture in his right shoulder blade during the fight and would require six months to recover from the injury.[3] Despite the loss Marquez expressed his eagerness to face Lopez in a rematch.[4]
Rafael MárquezLopez defeated Marquez via technical knockout in the eighth round. Marquez was unable to continue following the eighth round citing a shoulder injury.
Allan Green vs. 
Glen JohnsonJohnson defeats Green via knockout in the eighth round.
Marvin Quintero vs. 
Daniel AttahAttah defeated Quintero via knockout in the second round.
Diego Magdaleno vs. Derrick CamposMagdaleno defeated Campos via technical knockout in the fourth round.
Mickey Bey vs. Eric CruzBey Jr defeated Cruz via unanimous decision (60-53, 59-53, 59-53).
Cesar GrajedaArroyo defeated Grajeda via technical knockout in the first round.
Dany Escobar vs. Anthony LenkLenk defeated Escobar via unanimous decision.
Jesus Magdaleno vs. Matthew SalazarMagdaleno defeated Salazar via technical knockout in the first round. This was Magdaleno's professional debut.
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| align=left | SuperSport 1 | ||
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| align=left | Canal 5 | ||
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| HBO PPV | |||
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