| Juan Manuel Alejándrez | |
| Fullname: | Juan Manuel Alejándrez Rodríguez |
| Birth Date: | 17 May 1944 |
| Birth Place: | San Pedro Tesistan, Jalisco, Mexico |
| Position: | Defender |
| Years1: | 1964–1965 |
| Years2: | 1965–1973 |
| Years3: | 1973–1977 |
| Years4: | 1977–1978 |
| Clubs1: | Club Deportivo Nacional |
| Clubs2: | Cruz Azul |
| Clubs3: | CD Oro |
| Clubs4: | Atlante |
| Nationalyears1: | 1967–1970 |
| Nationalteam1: | Mexico |
| Nationalcaps1: | 24 |
| Nationalgoals1: | 0 |
Juan Manuel Alejándrez Rodríguez (May 17, 1944 – January 6, 2007) was a Mexican football defender. He played for the Mexico national team between 1967 and 1970, including the World Cup on home soil in 1970.