| Juan José Ossa | |
| Office: | Minister Secretary-General of the Presidency |
| Term Start: | 6 January 2021 |
| Term End: | 11 March 2022 |
| President: | Sebastián Piñera |
| Predecessor: | Cristián Monckeberg |
| Successor: | Giorgio Jackson |
| Office1: | General Undersecretary of the Presidency |
| Term Start1: | 1 January 2020 |
| Term End1: | 6 January 2021 |
| Predecessor1: | Juan Francisco Galli |
| Successor1: | Maximo Pávez |
| Office2: | Undersecretary of Justice |
| Term Start2: | 11 March 2018 |
| Term End2: | 1 January 2020 |
| Predecessor2: | Nicolás Mena Letelier |
| Successor2: | Sebastián Valenzuela Agüero |
| Birth Date: | 1979 9, df=y |
| Birth Place: | Santiago, Chile |
| Party: | Renovación Nacional[1] |
| Occupation: | Politician |
| Profession: | Lawyer |
| Parents: | Juan Luis Ossa Lucía Santa Cruz[2] |
| Spouse: | Carmen Lyon |
| Children: | Three |
Juan José María Santa Cruz (born 12 September 1979) is a Chilean lawyer and politician. He served as the Ministry General Secretariat of the Presidency from 2021 to 2022.[3] In 2018, he was appointed by Sebastián Piñera as Undersecretary of Justice[4] and in 2020 was appointed as General Undersecretariat of the Presidency.[5]