| Juan Francisco Giró | |
| Office: | President of Uruguay |
| Term Start: | 1 March 1852 |
| Term End: | 25 September 1853 |
| Predecessor: | Bernardo Berro |
| Successor: | Venancio Flores |
| Birth Date: | June 3, 1791 |
| Birth Place: | Montevideo, Uruguay |
| Death Date: | May 8, 1863 (aged 71) |
| Party: | National Party |
| Profession: | Politician |
Juan Francisco Giró (3 June 1791, Montevideo - 8 May 1863) was a Uruguayan politician and the President of Uruguay from 1852 until 1853.
He was deposed by a military mutiny in September 1853 by one of the Colorado party.