| Josias Hendrik Otto du Plessis | |
| Office: | Administrator of the Cape Province |
| Term Start: | 12 May 1958 |
| Term End: | 28 April 1960 |
| Predecessor: | P.J. Olivier |
| Successor: | Nico Malan |
| Office2: | Member of Parliament for Stellenbosch |
| Term Start2: | 15 April 1953 |
| Term End2: | 11 May 1959 |
| Predecessor2: | J.A. Loubser |
| Successor2: | Hennie Smit |
| Birth Date: | 1907 2, df=yes |
| Birth Place: | Vanrhynsdorp, Cape Colony |
| Death Place: | Cape Town, Cape Province, South Africa |
| Party: | National |
| Spouse: | Bernice |
| Children: | 3 |
| Residence: | Leeuwenhof |
Josias Hendrik Otto du Plessis (23 February 1907 - 1960) was Administrator of the Cape Province in South Africa from 1953 to 1958.
He was born in Vanrhynsdorp and was elected as a Member of Parliament for Stellenbosch in 1953.[1]
. Encyclopedia of Southern Africa. Eric Rosenthal (historian). 1978.