| Joseph Guillaume Bossé | |
| Constituency Mp: | Quebec-Centre |
| Parliament: | Canadian |
| Predecessor: | Jacques Malouin |
| Successor: | François Langelier |
| Term Start: | 1882 |
| Term End: | 1887 |
| Birth Date: | 4 August 1843 |
| Birth Place: | Quebec, Canada East |
| Death Place: | Unknown |
| Nationality: | British subject |
| Party: | Conservative Party |
| Occupation: | lawyer |
Joseph Guillaume Bossé (born August 4, 1843 in Quebec, Canada East-died September 7, 1908) was a politician and lawyer. He was elected to the House of Commons of Canada in 1882 as a Member of the Conservative Party to represent the riding of Quebec-Centre. His father was Senator Joseph-Noël Bossé (1807–1881).