| Josefina Cota Cota | |
| Office: | Member of the Senate for Baja California Sur |
| Term Start: | 1 September 2006 |
| Term End: | 31 August 2012 |
| Predecessor: | Ricardo Gerardo Higuera |
| Successor: | Isaías González Cuevas |
| Office2: | Member of the Chamber of Deputies for Baja California Sur′s 2nd district |
| Term Start2: | 19 October 2004 |
| Term End2: | 31 August 2006 |
| Predecessor2: | Narciso Agúndez Montaño |
| Successor2: | Víctor Manuel Lizárraga |
| Birth Date: | 1956 6, df=yes |
| Birth Place: | La Paz, Baja California Sur, Mexico |
| Occupation: | Senator |
Josefina Cota Cota (born 3 June 1956) is a Mexican politician affiliated with the PRD. She served as Senator of the LX and LXI Legislatures of the Mexican Congress representing Baja California Sur.[1] She previously served in the Congress of Baja California Sur from 1987 to 1991.[1]