| Jose Ledesma | |
| Office1: | Senator of the Philippines from the 7th District |
| Term Start1: | 21 July 1927 |
| Term End1: | 2 June 1931 |
| Alongside1: | Jose Hontiveros Antonio Belo |
| Predecessor1: | Jose Maria Arroyo |
| Successor1: | Ruperto Montinola |
| Office2: | Governor of Iloilo |
| Term Start2: | 1945 |
| Term End2: | 1945 |
| Predecessor2: | Patricio Confesor |
| Successor2: | Tomas Vargas |
| Term Start3: | 1925 |
| Term End3: | 1927 |
| Predecessor3: | Ruperto Montinola |
| Successor3: | Jose Lopez-Vito |
| Party: | Nacionalista |
Jose B. Ledesma was a Filipino politician.
Jose Ledesma completed a bachelor's degree in law and passed the Philippine bar entrance exam in 1912. From the same year he was also a member of the Iloilo Provincial Board. From 1925 to 1927 he was governor of Iloilo. When Senator Jose Maria Arroyo died in 1927, Ledesma was elected during a special election on July 21, 1927, for the remainder of his term in the Philippine Senate as representative of the 7th District until 1931.[1] After the Second World War, Ledesma was appointed acting governor of Iloilo in 1946.