| Jose de Jesus | |
| Realname: | Jose De Jesus |
| Nickname: | Cagüitas |
| Weight: | Light flyweight |
| Nationality: |  Puerto Rican |
| Birth Date: | 12 August 1963 |
| Birth Place: | Cayey, Puerto Rico |
| Total: | 41 |
| Wins: | 31 |
| Losses: | 9 |
| Draws: | 1 |
| No Contests: | 0 |
| Ko: | 22 |
Jose De Jesus (born August 12, 1963 in Cayey, Puerto Rico) is a retired professional boxer in the light flyweight (108 lb) division.
Nicknamed "Cagüitas", De Jesus became the first WBO light flyweight champion on May 19, 1989. He defended this title three times, but was stripped of it in March 1992 for failure to defend.