| José Luis Mosquera | |
| Fullname: | José Luis Mosquera Moreno |
| Birth Date: | 14 March 1995 |
| Birth Place: | Turbo, Colombia |
| Position: | defender |
| Years1: | 2017–2019 |
| Caps1: | 59 |
| Goals1: | 4 |
| Years2: | 2020–2021 |
| Clubs2: | Leones |
| Caps2: | 10 |
| Goals2: | 0 |
| Years3: | 2021–2022 |
| Caps3: | 8 |
| Goals3: | 0 |
| Caps4: | 0 |
| Goals4: | 0 |
| Years4: | 2022–2023 |
| Club-Update: | 27 March 2023 |
José Luis Mosquera Moreno (born 14 March 1995) is a Colombian professional footballer who last played as a defender for Bangladesh Premier League club AFC Uttara.